Empowering women, reducing poverty and improving the overall health
and well-being of women and children are noble goals. As with all great
visions, however, the devil is in the details. Melinda Gates claims that the key to reducing poverty is to flood the developing world with contraceptives and abortifacients.
A cornerstone of this effort is the development of a new injectable
contraceptive that would be analogous to the currently available
medroxyprogesterone acetate also known as DMPA, or by its brand name
Depo-Provera. Unlike Depo Provera, which requires an intramuscular
injection and must be administered by a medical professional, this new
form is a self-administered subcutaneous injection. Ms. Gates hopes that
her efforts will bring contraception to at least an additional 120
million women worldwide, with the primary focus being in sub-Saharan
African and South Asia.
But what exactly is Ms. Gates offering these women? Her “solution”
will result in the death of countless newly conceived children, it may
double the transmission rates of HIV and it will certainly increase the
risks for breast cancer. In addition, progestin-only contraceptives are
associated with a significant risk for blood clots and strokes.
There are two mechanisms of action for injectable contraceptives like
Depo Provera to prevent pregnancy. The first is to prevent ovulation
so that conception does not occur. However, if this mechanism is
unsuccessful and conception does occur, Depo Provera keeps the lining of
the uterus so thin that implantation will not occur. The result is
that the newly conceived life is aborted.
In promoting her cause, Ms. Gates links her efforts to expand
contraceptive use to the fight against HIV/AIDS. However, use of an
injectable contraception offers no protection against HIV transmission.
In fact, researchers from the University of Washington studied women in
Africa and found that the use of DMPA doubled the transmission rates of HIV.
They cited three mechanisms to account for this increase. First, the
hormonal contraceptives cause the vaginal lining to thin and develop
small tears that increase the exposure to HIV during sex. Secondly, the
hormonal contraceptives weaken the immune system and reduce a woman’s
ability to repel HIV infection. Finally, women who are HIV positive and
take hormonal contraceptives shed more HIV virus, making them more
infectious.
Clearly, increased use of an injectable hormonal contraceptive is not going to help the fight against AIDS.
Hormonal contraceptives are also associated with a significantly increased risk of breast cancer. In a 2012 study published in the Journal of Cancer Research,
researchers from the Fred Hutchinson Cancer Research Center looked
specifically at DMPA and found that it doubled the risk of breast
cancer. Pushing for expanded use of a drug that doubles the breast
cancer risk in developing countries with limited capacity for routine
screening for breast cancer is illogical and borders on reckless. So why
would the Gates Foundation advocate such a medically risky solution to
the poverty of developing countries?
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